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What is Durolane 1×3 ml? Durolane 60mg is a thick, transparent gel made up of highly-purified sodium hyaluronate (hyaluronic acid). Sodium hyaluronate is found throughout the body, but specifically in joint tissue and the fluid that surrounds it. In the knee joint, this naturally occurring linear polymer works as a lubricant and shock absorber. The content of sodium hyaluronate, as well as its ability to lubricate and cushion, may be diminished in joints damaged by osteoarthritis. A single injection of Durolane 60mg directly into the joint may improve lubrication and cushioning, thus reducing pain associated with movement.